Research Article
Establishment of an Immune-Related Gene Signature for Risk Stratification for Patients with Glioma
Table 4
The correlations between the risk score and clinicopathological characteristics.
| | Characteristics | TCGA cohort () | CGGA cohort () | | High risk | Low risk | value | High risk | Low risk | value |
| | Age | | | | | | | | <60 | 189 | 342 | | 159 | 203 | | | ≥60 | 120 | 37 | | 46 | 13 | | | NA | — | — | | 1 | — | | | Gender | | | 0.8164 | | | 0.4308 | | Female | 131 | 165 | | 83 | 96 | | | Male | 178 | 214 | | 123 | 120 | | | Tumor grade | | | | | | | | Low | 149 | 374 | | 93 | 189 | | | High | 160 | 5 | | 113 | 27 | | | IDH status | | | | | | | | Mutation | 78 | 356 | | 66 | 142 | | | Wild-type | 223 | 21 | | 137 | 38 | | | NA | 8 | 2 | | 3 | 36 | | | MGMT promoter status | | | | | | 0.2748 | | Methylation | 148 | 339 | | 90 | 107 | | | Unmethylation | 124 | 39 | | 76 | 70 | | | NA | 37 | 1 | | 40 | 39 | |
|
|
TCGA: The Cancer Genome Atlas; CGGA: Chinese Glioma Genome Atlas; IDH: isocitrate dehydrogenase; MGMT: O-6-methylguanine-DNA methyltransferase; NA: not available; bold texts indicate statistically significant difference.
|