Research Article
Comprehensive Analysis of Pertinent Genes and Pathways in Atrial Fibrillation
Table 1
Log-fold changes of the top10 upregulated DEGs and top10 downregulated DEGs in the sinus rhythm control group and atrial fibrillation patient samples.
| Gene symbol | Gene title | log2 FC | | Expression |
| SEL1L3 | SEL1L family member 3 | 0.060340007 | | Upregulated | DHRS9 | Dehydrogenase/reductase 9 | 0.188569525 | | Upregulated | FLT4 | Fms-related tyrosine kinase 4 | 0.099135639 | | Upregulated | BICD1 | BICD cargo adaptor 1 | 0.163528177 | | Upregulated | LINC00608 | Long intergenic non-protein-coding RNA 608 | 0.043723792 | | Upregulated | RNF216 | Ring finger protein 216 | 0.074128631 | | Upregulated | DHRS13 | Dehydrogenase/reductase 13 | 0.045246216 | | Upregulated | PRR11 | Proline-rich 11 | 0.056029931 | | Upregulated | MAD2L2 | MAD2 mitotic arrest deficient-like 2 (yeast) | 0.040471973 | | Upregulated | ATP1B4 | ATPase Na+/K+ transporting family member beta 4 | 0.307563341 | | Upregulated | GALNT16 | Polypeptide N-acetylgalactosaminyltransferase 16 | -0.098686876 | | Downregulated | HCN4 | Hyperpolarization-activated cyclic nucleotide-gated potassium channel 4 | -0.082582678 | | Downregulated | MASP1 | Mannan-binding lectin serine peptidase 1 | -0.102728211 | | Downregulated | LGR6 | Leucine-rich repeat-containing G protein-coupled receptor 6 | -0.103112526 | | Downregulated | LOC102725271///NTM | Neurotrimin-like///neurotrimin | -0.202137537 | | Downregulated | CLSTN2 | Calsyntenin 2 | -0.131561085 | | Downregulated | TMEM245 | Transmembrane protein 245 | -0.089869756 | | Downregulated | BTBD7 | BTB domain-containing 7 | -0.073546467 | | Downregulated | ZNF521 | Zinc finger protein 521 | -0.095026053 | | Downregulated | FNDC5 | Fibronectin type III domain-containing 5 | -0.076766249 | | Downregulated |
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