Research Article

Comprehensive Analysis of Pertinent Genes and Pathways in Atrial Fibrillation

Table 1

Log-fold changes of the top10 upregulated DEGs and top10 downregulated DEGs in the sinus rhythm control group and atrial fibrillation patient samples.

Gene symbolGene titlelog2 FCExpression

SEL1L3SEL1L family member 30.060340007Upregulated
DHRS9Dehydrogenase/reductase 90.188569525Upregulated
FLT4Fms-related tyrosine kinase 40.099135639Upregulated
BICD1BICD cargo adaptor 10.163528177Upregulated
LINC00608Long intergenic non-protein-coding RNA 6080.043723792Upregulated
RNF216Ring finger protein 2160.074128631Upregulated
DHRS13Dehydrogenase/reductase 130.045246216Upregulated
PRR11Proline-rich 110.056029931Upregulated
MAD2L2MAD2 mitotic arrest deficient-like 2 (yeast)0.040471973Upregulated
ATP1B4ATPase Na+/K+ transporting family member beta 40.307563341Upregulated
GALNT16Polypeptide N-acetylgalactosaminyltransferase 16-0.098686876Downregulated
HCN4Hyperpolarization-activated cyclic nucleotide-gated potassium channel 4-0.082582678Downregulated
MASP1Mannan-binding lectin serine peptidase 1-0.102728211Downregulated
LGR6Leucine-rich repeat-containing G protein-coupled receptor 6-0.103112526Downregulated
LOC102725271///NTMNeurotrimin-like///neurotrimin-0.202137537Downregulated
CLSTN2Calsyntenin 2-0.131561085Downregulated
TMEM245Transmembrane protein 245-0.089869756Downregulated
BTBD7BTB domain-containing 7-0.073546467Downregulated
ZNF521Zinc finger protein 521-0.095026053Downregulated
FNDC5Fibronectin type III domain-containing 5-0.076766249Downregulated