[Retracted] Detection of BRCA1/2 Mutation and Analysis of Clinicopathological Characteristics in 141 Cases of Ovarian Cancer

Table 1

Showing the details of ClinVar pathogenic mutations in BRCA1 and BRCA2 genes in 141 patients with ovarian cancer.

Patient ID	Tissue type	Gene	Exon	Mutated site	Protein	Variant types
1	Tumor tissue	BRCA1	10	c.3286C>T	p.Gln1096Ter	Nonsense
2	Tumor tissue	BRCA1	10	c.784C>T	p.Gln262Ter	Nonsense
3	Tumor tissue	BRCA1	10	c.3214delC	p.Leu1072Ter	Nonsense
4	Peripheral blood	BRCA1	10	c.2110_2111del	p.Asn704Cysfs7	Frameshift
5	Tumor tissue	BRCA1	10	c.2110_2111del	p.Asn704Cysfs7	Frameshift
6	Peripheral blood	BRCA1	10	c.4065_4068del	p.N1355Kfs10	Frameshift
7	Tumor tissue	BRCA1	10	c.4065_4068del	p.N1355Kfs10	Frameshift
8	Tumor tissue	BRCA1	10	c.2388_2389del	p.Thr796fs	Frameshift
9	Tumor tissue	BRCA1	10	c.3868dupA	p.C1291Mfs4	Frameshift
10	Tumor tissue	BRCA1	10	c.1504_1508del	p.Leu502fs	Frameshift
11	Peripheral blood	BRCA1	10	c.2889_2890del	p.G964Tfs6	Frameshift
12	Tumor tissue	BRCA1	10	c.1276del	p.S426Qfs4	Frameshift
13	Tumor tissue	BRCA1	10	c.2302delA	p.Ser768Valfs24	Frameshift
14	Tumor tissue	BRCA1	12	c.4357+1G>A	/	Splicing mutation
15	Tumor tissue	BRCA1	13	c.4485-2A>C	/	Splicing mutation
16	Tumor tissue	BRCA1	14	c.4566G>C	p.Tyr1522Ter	Nonsense
17	Tumor tissue	BRCA1	15	c.4756G>T	p.Glu1586Ter	Nonsense
18	Tumor tissue	BRCA1	23	c.5468-2A>G	/	Splicing mutation
19	Tumor tissue	BRCA1	23	c.5511_5524del	p.W1837Cfs38	Deletion
20	Tumor tissue	BRCA2	9	c.755_758del	p.Asp252Valfs24	Frameshift
21	Tumor tissue	BRCA2	11	c.3109C>T	p.Gln1037Ter	Nonsense
22	Peripheral blood	BRCA2	11	c.3109C>T	p.Gln1037Ter	Nonsense
23	Tumor tissue	BRCA2	11	c.C3523T	p.Gln1175Ter	Nonsense
24	Tumor tissue	BRCA2	11	c.5576_5579delTTAA	p.Idel1859Lysfs	Frameshift
25	Tumor tissue	BRCA2	11	c.5164_5165delAG	p.Ser1722Tyrfs	Frameshift
26	Tumor tissue	BRCA2	11	c.2176delG	p.V726Ffs4	Frameshift
27	Peripheral blood	BRCA2	22	c.8915delT	p.leu2972Cysfs4	Deletion