Research for Expression and Prognostic Value of GABRD in Colon Cancer and Coexpressed Gene Network Construction Based on Data Mining

Figure 3

Genes related to GABRD expression in colon cancer. (a) Volcano plot of Pearson correlation of GABRD and the differentially expressed genes in the CPTAC-COAD dataset. The green dots represent the genes significantly negatively correlated with GABRD; the red dots represent the genes notably positively correlated with GABRD; the black dots are the genes not significantly correlated with GABRD; (b, c) expression of the genes remarkably positively correlated with GABRD and negatively correlated with GABRD demonstrated in two heat maps, respectively (top 50 genes were selected according to value); (d) coexpressed genes of GABRD in colon cancer were analyzed by GO annotation; (e) KEGG pathway enrichment analysis was conducted on the coexpressed genes of GABRD.

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