MMP1 Overexpression Promotes Cancer Progression and Associates with Poor Outcome in Head and Neck Carcinoma

Table 1

The associations between MMP1 expression and multiple clinicopathological parameters in HNSCC samples.

Clinicopathological parameters	Cases	MMP1		-values
		Low	High
Gender	103	40	63
Male	54	23	31	0.4269
Female	49	17	32
Age
≤60	43	18	25	0.6829
>60	60	22	38
Smoking
No	75	30	45	0.8211
Yes	28	10	18
Alcohol use
No	61	20	41	0.1526
Yes	42	20	22
Tumor size
T1-T2	69	33	36	0.0097
T3-T4	34	7	27
Pathological grade
I	66	34	32	0.0006
II	17	5	12
III	20	1	19
Cervical node metastasis
N(0)	71	33	38	0.0280
N(+)	32	7	25
Clinical stage
I	18	8	10	0.2842
II	53	20	33
III	20	10	10
IV	12	2	10

indicate statistical significance with -values less than 0.05.