[Retracted] Study on the Mechanism of Treating Femoral Head Necrosis with Drynariae Rhizoma Based on Network Pharmacology

Table 2

Active ingredients and key targets of Drynariae Rhizoma in treating ONFH.

No.	Active ingredients	Key targets
1	Luteolin	MMP1, MMP2, and MMP13
2	Beta-sitosterol	AR, CYP19A1, CYP17A1, LDLR, ESR1, and ESR2
3	Cyclolaudenol	LDLR, HSD11B1, and UGT2B17
4	22-Stigmasten-3-one	TRPV1, TRPV4, and CYP19A1
5	Cycloartenone	CYP19A1, TRPV1, TRPV4, CYP17A1, and NR3C1
6	Xanthogalenol	CYP19A1 and NOS3
7	Eriodyctiol (flavanone)	CYP1B1, CYP1A1, CYP19A1, MMP1, and MMP13
8	Kaempferol	ABCB1, HSD17B1, ALOX15, ALOX12, and CYP1B1
9	Stigmasterol	AR, CYP19A1, LDLR, CYP17A1, ESR1, and ESR2
10	Aureusidin	ERBB2
11	(+)-catechin	CA2
12	Naringenin	CYP19A1, HSD17B1, CYP1B1, CYP1A1, and ESR1
13	Digallate	CA2
14	Davallioside A_qt	MMP2 and CA2
15	Marioside_qt	STAT1 and MMP2
16	Eriodictyol	CYP1B1, CYP1A1, CYP19A1, MMP1 and MMP13