Integrated Analysis and Validation of Autophagy-Related Genes and Immune Infiltration in Acute Myocardial Infarction

Figure 2

Identification of differentially expressed autophagy-related genes in AMI patients. (a) Volcano plot of differentially expressed genes between the two groups of samples in GSE61144. The red points represent upregulated genes screened on the basis of with an adj. value <0.05. The green points represent downregulated genes screened on the basis of with an adj. value <0.05. The black dots represent genes with no significant difference. FC is the fold change. (b) Venn diagram of the intersection of DEmRNAs and ARGs in HADb. The dark area in the middle represents DEARGs that were identified by analysis of DEmRNAs (left, purple) and ARGs in the Human Autophagy Database (HADb) (right, orange). (c) Heat map of DEARGs. Red indicates that gene expression is relatively upregulated, green indicates gene expression is relatively downregulated, and black indicates no significant change in gene expression.

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