Integrative Analyses of Biomarkers Associated with Endoplasmic Reticulum Stress in Ischemic Stroke

Figure 3

GO/KEGG enrichment analyses of ERS-DEGs. (a) Advanced bubble chart shows GO functional enrichment significance items of ERS-DEGs in three functional groups: BP, MF, and CC. The -axis and -axis labels represent the gene ratios enriched in the GO analysis group and GO terms, respectively. The color of dots represents the adjusted value: the redder the color, the lesser the adj. value; the bluer the color, the greater the adj. value. The size of dots represents gene counts. (b–d) Chord diagrams show the distribution of ERS-DEGs in the three different GO-enriched functions. The color of dots represents the log FC of the genes. (e) Advanced bubble chart shows enrichment of ERS-DEGs in signal pathways. (f) The chord diagram shows the distribution of ERS-DEGs in different KEGG pathways. (g) The pathway diagram shows the immune response-activating cell surface receptor signaling pathway with the highest enrichment degree in GO analysis. (h) The pathway diagram shows that the leishmaniasis pathway has the highest enrichment degree in KEGG analysis.

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