Bioinformatics Analysis Revealing the Correlation between NF-κB Signaling Pathway and Immune Infiltration in Gastric Cancer

Figure 2

GC samples were clustered by NF-κB signaling pathway score. (a) The expression of NF-κB-related genes in GC samples. (b) GC samples were divided into two cluster (C1 and C2 type) based on NF-κB signaling pathway score (setting median value as cutoff). The bar charts showed the proportions of different grade, T, pathology, and stage in C1 and C2 type. (c) Volcano plot showed the DEGs between C1 and C2 type. The labeled items were immune checkpoint-related genes. (d) Volcano plot showed differential biological processes analyzed by GSVA between C1 and C2 type. (e) GSEA showed that multiple immune-related biological processes were enriched in C2 type. GC: gastric cancer; DEGs: differential expressed genes; GSVA: gene set variation analysis; GSEA: gene set enrichment analysis.

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