Identification of the Key Genes Involved in the Tumorigenesis and Prognosis of Prostate Cancer

Figure 6

Validation of TOP2A, NCAPG, and BUB1B using survival analysis and ROC curve. (a) The correlation between TOP2A, NCAPG, and BUB1B overall survival time is based on the best separation in the TCGA-PRAD dataset (internal validation dataset). (b) Receiver operating characteristic (ROC) curves and area under the curve (AUC) statistics were undertaken to evaluate the ability of hub genes to distinguish PCa from normal samples with significant specificity and sensitivity in the TCGA dataset.

(a)

(b)