Identification of the Key Genes Involved in the Tumorigenesis and Prognosis of Prostate Cancer

<div>The mRNA expression patterns, genomic alterations, and methylation of the three hub genes. (a) The genetic alterations of the three hub genes based on the cBioPortal. The primary mutation types of the three hub genes were AMP, diploid, and deep deletion. BUB1B has the highest mutation rate (6%), while NCAPG and TOP2A have a 4% mutation rate. (b) Alteration frequency analysis of the three hub genes in TCGA-PRAD using the cBioPortal.</div>

Computational and Mathematical Methods in Medicine

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Figure 9

Figure 9: Identification of the Key Genes Involved in the Tumorigenesis and Prognosis of Prostate Cancer 