Computational and Mathematical Methods in Medicine

Research Article

A Four-Gene Signature Associated with Radioresistance in Head and Neck Squamous Cell Carcinoma Identified by Text Mining and Data Analysis

The top six gene ontology enrichment terms of identified four genes (terms that do not meet the value < 0.05 conditions are not shown).


Category	Term	Description	Count	Gene	value

GOTERM_BP_FAT	GO:0022603	Regulation of anatomical structure morphogenesis	4	SERPINE1, SPP1, VEGFC, EPHB2
GOTERM_BP_FAT	GO:0051240	Positive regulation of multicellular organismal process	4	SERPINE1, SPP1, VEGFC, EPHB2
GOTERM_BP_FAT	GO:2000026	Regulation of multicellular organismal development	4	SERPINE1, SPP1, VEGFC, EPHB2	0.001102607
GOTERM_BP_FAT	GO:0001525	Angiogenesis	3	SERPINE1, VEGFC, EPHB2	0.001811168
GOTERM_BP_FAT	GO:0009605	Response to external stimulus	4	SERPINE1, SPP1, VEGFC, EPHB2	0.001927546
GOTERM_BP_FAT	GO:0048514	Blood vessel morphogenesis	3	SERPINE1, VEGFC, EPHB2	0.002552747
GOTERM_CC_FAT	GO:0031093	Platelet alpha granule lumen	2	SERPINE1, VEGFC	0.011315988
GOTERM_CC_FAT	GO:0031091	Platelet alpha granule	2	SERPINE1, VEGFC	0.01540963
GOTERM_CC_FAT	GO:0034774	Secretory granule lumen	2	SERPINE1, VEGFC	0.017656309
GOTERM_CC_FAT	GO:0060205	Cytoplasmic membrane-bounded vesicle lumen	2	SERPINE1, VEGFC	0.021528882
GOTERM_CC_FAT	GO:0031983	Vesicle lumen	2	SERPINE1, VEGFC	0.021732419
GOTERM_CC_FAT	GO:0005615	Extracellular space	3	SERPINE1, SPP1, VEGFC	0.027662649
GOTERM_MF_FAT	GO:0005102	Receptor binding	4	SERPINE1, SPP1, VEGFC, EPHB2