Research Article

Identifying and Classifying Enhancers by Dinucleotide-Based Auto-Cross Covariance and Attention-Based Bi-LSTM

Table 1

The independent test performance comparison of this model with other models.

MethodACC (%)SN (%)SP (%)MCC

Enhancer identification
 EnhancerPred74.0073.5074.500.4800
 iEnhancer-2L73.0071.0075.000.4604
 iEnhancer-EL74.7571.0078.500.4964
 Enhancer-5Step79.0082.0076.000.5800
 Tan et al.75.5075.5076.000.5100
 iEnhancer-ECNN76.9078.5075.200.5370
 iEnhancer-CNN77.5078.2579.000.5850
Our method77.2577.3077.200.5470
Enhancer classification
 EnhancerPred55.0045.0065.000.1021
 iEnhancer-2L60.5047.0074.000.2181
 iEnhancer-EL78.0354.0068.000.2222
 Enhancer-5Step63.5074.0053.000.2800
 Tan et al.68.4983.1545.610.3120
 iEnhancer-ECNN67.8079.1056.400.3680
 iEnhancer-CNN75.0065.2576.100.3232
Our method73.5087.0060.000.4881