Research Article
Circular RNA CCDC66 Improves Murine Double Minute 4 (MDM4) Expression through Targeting miR-370 in Colorectal Cancer
Figure 5
circCCDC66 promoted the progression of CRC cells via the miR-370/MDM4 axis. (a, b) Compared with NC, the number of clones in MDM4-siRNA or miR-370 mimics transfected cells was significantly reduced. (c, d) MDM4-siRNA or miR-370 mimics reduced the migration in HCT-116 and RKO cells. (e, f) MDM4-siRNA or miR-370 mimics reduced the invasion in HCT-116 and RKO cells. , .
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