Computational Modeling of T Cell Hypersensitivity during Coronavirus Infections Leading to Autoimmunity and Lethality

Figure 6

Closed-state SARS-CoV-2 (PDB ID: 6VYB) docked in the retinal CD147 receptor (PDB ID: 3QR2) with crystallographic water molecules: (a) the best binding mode in the receptor, (b) the best binding mode in the receptor along with side chains as lines, and (c) the best twenty binding modes showing amino acid residues involved in the interactions at 5 Å distance (receptor in cyan, ligand as dark blue sticks, and interactions as yellow dashes).

(a)

(b)

(c)