Review Article
A Structured Review of Quantitative Models of the Pharmaceutical Supply Chain
Table 1
Quantitative models of supply chain network design.
| Author | Source of uncertainty | Type of demand | Number of medicines | Supply chain components | Methodology |
| Rotstein et al. (1999) | Consumption of manufacturing resources | Deterministic | 8 | Manufacture | Stochastic programming |
| Papageorgiou et al. (2001) | | Deterministic | 7 | Manufacture | Optimization |
| Levis and Papageorgiou (2003) | | Deterministic | 7 | Manufacture | Optimization Heuristic |
| Levis and Papageorgiou (2004) | Clinical trials outcomes | Deterministic | 7 | Manufacture | Optimization heuristic |
| Gatica et al. (2003a) | Demand | Deterministic stochastic | 12 | Manufacture | Optimization |
| Gatica et al. (2003b) | Demand | Deterministic and stochastic | 12 | Manufacture | Heuristic |
| Chambers et al. (2009) | Demand and technical aspects | Stochastic | 5 | Manufacture | Stochastic dynamic optimization |
| Susarla and Karimi (2012) | | Deterministic | 8 | Manufacture Warehouse Waste treatment plant | Optimization |
| Mousazadeh et al. (2015) | Demand costs | Stochastic | 1 | Manufacture distribution center | Multiobjective optimization |
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