Research Article

Selective Phenome Growth Adapted Model: A Novel Landscape to Represent Aptamer Ligand Binding

Figure 6

Comparison of mean path divergences among theoretical and empirical landscapes: mean path divergences, a measure of landscape smoothness, were compared between theoretical and empirical landscapes. The empirical landscape was binding data (black squares) for 10-base aptamers against the protein allophycocyanin [41]. The theoretical landscapes were genome-selected [34] (blue triangles) and the novel ones were phenome-selected (red circles), both with a string size of in order to correspond with the empirical dataset. The phenome selected landscape is more similar to the empirical dataset.