Hypergraph Regularized Discriminative Nonnegative Matrix Factorization on Sample Classification and Co-Differentially Expressed Gene Selection

Table 7

Unique co-differentially expressed genes by HDNMF (INTA 1).

Official gene symbol	Official name	Related diseases	Related GO annotations	RS	Paralog gene
ERBB3	Erb-B2 receptor tyrosine kinase 3	Retroperitoneal leiomyosarcoma and fatal congenital contracture syndrome 2	Protein homodimerization activity and transferase activity, transferring phosphorus-containing groups	94.06	ERBB4
CTSC	Cathepsin C	Papillon-Lefevre syndrome and Haim-Munk syndrome	Identical protein binding and cysteine-type peptidase activity	76.89	TINAGL1
AGT	Angiotensinogen	Renal tubular dysgenesis and hypertension, essential	Growth factor activity and serine-type endopeptidase inhibitor activity	65.57	Null
RHOC	Ras homolog family member C	Breast disease and breast cancer	GTP binding and obsolete signal transducer activity	64.59	RHOA
HP	Haptoglobin	Anhaptoglobinemia and Plasmodium falciparum malaria	Serine-type endopeptidase activity and hemoglobin binding	59.62	HPR
BCL2L1	BCL2-like 1	B-cell lymphomas and follicular lymphoma	Protein homodimerization activity and protein heterodimerization activity	49.62	BCL2
ABCC3	ATP binding cassette subfamily C member 3	Dubin-Johnson syndrome and extrahepatic cholestasis	Transporter activity and ATPase activity	46.90	ABCC1