Research Article
Dynamic Modeling of the Angiogenic Switch and Its Inhibition by Bevacizumab
Table 6
Sensitivities (
) of the model to the changes of parameters
, , , , , , , , , and
in the case of therapy 1. One unit is
.
| | -20% | -10% | -5% | +5% | +10% | +20% |
| | 0.2926 | 0.0525 | 0.0114 | 0.0086 | 0.0305 | 0.0975 | | 0.9383 | 0.3259 | 0.0962 | 0.1353 | 0.6422 | 3.6265 | | 0.1375 | 0.0368 | 0.0095 | 0.0102 | 0.0420 | 0.1807 | | 0.0181 | 0.0043 | 0.0011 | 0.0010 | 0.0039 | 0.0149 | | 0.4498 | 0.1518 | 0.0442 | 0.0611 | 0.2889 | 1.6242 | | 0.4594 | 0.1559 | 0.0456 | 0.0634 | 0.3011 | 1.7086 | | 0.9364 | 0.1493 | 0.0305 | 0.0213 | 0.0720 | 0.2128 | | 0.0100 | 0.0023 | 0.0005 | 0.0005 | 0.0019 | 0.0069 |
|
|