Table of Contents
Conference Papers in Medicine
Volume 2013 (2013), Article ID 879513, 4 pages
http://dx.doi.org/10.1155/2013/879513
Conference Paper

Hyperfractionated Thermoradiotherapy Is More Effective and Less Invasive Than Radiation or Chemoradiation in Heatable Cancers: A Meta-Analysis

Bicher Cancer Institute, 12099 W. Washington Boulevard, Los Angeles, CA 90066, USA

Received 24 January 2013; Accepted 8 July 2013

Academic Editors: G. Baronzio, M. Jackson, D. Y. Lee, and A. Szasz

This Conference Paper is based on a presentation given by Haim I. Bicher at “Conference of the International Clinical Hyperthermia Society 2012” held from 12 October 2012 to 14 October 2012 in Budapest, Hungary.

Copyright © 2013 Haim I. Bicher. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. G. Arcangeli, E. Barni, and A. Cividalli, “Effectiveness of microwave hyperthermia combined with ionizing radiation: clinical results on neck node metastases,” International Journal of Radiation Oncology, Biology, Physics, vol. 6, no. 2, pp. 143–148, 1980. View at Google Scholar · View at Scopus
  2. G. Arcangeli, A. Civadali, and G. Lovisolo, “The clinical use of experimental parameters to evaluate the response to combined heat and radiation,” in Proceeding of the 4th International Symposiumon Hyperthermic Oncology, J. Overgaard, Ed., vol. 1, pp. 329–335, Taylor & Francis, London, UK, 1984.
  3. G. Arcangeli, A. Cividalli, and C. Nervi, “Tumor control and therapeutic gain with different schedules of combined radiotherapy and local external hyperthermia in human cancer,” International Journal of Radiation Oncology, Biology, Physics, vol. 9, no. 8, pp. 1125–1134, 1983. View at Google Scholar · View at Scopus
  4. R. S. Scott, R. J. R. Johnson, H. Kowal, and H. I. Bicher, “Hyperthermia in combination with radiotherapy: a review of five years experience in the treatment of superficial tumors,” International Journal of Radiation Oncology, Biology, Physics, vol. 9, no. 9, pp. 1327–1333, 1983. View at Google Scholar · View at Scopus
  5. R. S. Scott, R. J. R. Johnson, K. V. Story, and L. Clay, “Local hyperthermia in combination with definitive radiotherapy: increased tumor clearance, reduced recurrence rate in extended follow-up,” International Journal of Radiation Oncology, Biology, Physics, vol. 10, no. 11, pp. 2119–2123, 1984. View at Google Scholar · View at Scopus
  6. R. Valdagni and M. Amichetti, “Report of long-term follow-up in a randomized trial comparing radiation therapy and radiation therapy plus hyperthermia to metastatic lymphnodes in stage IV head and neck patients,” International Journal of Radiation Oncology, Biology, Physics, vol. 28, no. 1, pp. 163–169, 1994. View at Google Scholar · View at Scopus
  7. H. I. Bicher, T. S. Sandhu, and F. W. Hetzel, “Hyperthermia and radiation in combination: a clinical fractionation regime,” International Journal of Radiation Oncology, Biology, Physics, vol. 6, no. 7, pp. 867–870, 1980. View at Google Scholar · View at Scopus
  8. H. I. Bicher, R. S. Wolfstein, and B. S. Lewinsky, “Microwave hyperthermia as an adjunct to radiation therapy: summary experience of 256 multifraction treatment cases,” International Journal of Radiation Oncology, Biology, Physics, vol. 12, no. 9, pp. 1667–1671, 1986. View at Google Scholar · View at Scopus
  9. J. Overgaard, D. G. Gonzalez, M. C. Hulshof et al., “Hyperthermia as an adjuvant to radiation therapy of recurrent or metastatic malignant melanoma. A multicentre randomized trial by the European Society for Hyperthermic Oncology,” International Journal of Hyperthermia, vol. 12, no. 1, pp. 3–20, 1996. View at Google Scholar · View at Scopus
  10. N. B. Hornback, R. E. Shupe, and H. Shidnia, “Advanced stage IIIB cancer of the cervix treatment by hyperthermia and radiation,” Gynecologic Oncology, vol. 23, no. 2, pp. 160–167, 1986. View at Google Scholar · View at Scopus
  11. D. S. Kapp, “Site and disease selection for hyperthermia clinical trials,” International Journal of Hyperthermia, vol. 2, no. 2, pp. 139–156, 1986. View at Google Scholar · View at Scopus
  12. R. Valdagni, F.-F. Liu, and D. S. Kapp, “Important prognostic factors influencing outcome of combined radiation and hyperthermia,” International Journal of Radiation Oncology, Biology, Physics, vol. 15, no. 4, pp. 959–972, 1988. View at Google Scholar · View at Scopus
  13. J. van der Zee, D. G. González, G. C. van Rhoon, J. D. P. van Dijk, W. L. J. van Putten, and A. A. M. Hart, “Comparison of radiotherapy alone with radiotherapy plus hyperthermia in locally advanced pelvic tumours: a prospective, randomised, multicentre trial,” The Lancet, vol. 355, no. 9210, pp. 1119–1125, 2000. View at Google Scholar · View at Scopus
  14. H. I. Bicher and N. Al-Bussam, “Thermoradiotherapy with curative intent—breast, head, neck and prostate tumors,” Deutsche Zeitschrift für Onkologie, vol. 38, no. 3, pp. 116–122, 2006. View at Publisher · View at Google Scholar · View at Scopus
  15. H. I. Bicher, “Thermoradiotherapy treatment of malignant tumors, fractionation regimen and objective and points,” Proceedings of the 26th Interantional Clinical Hyperthermia Society Meeting (ICHS '04), Shenzhen, China, September 2004.
  16. D. Algan, H. Fosmire, K. Hynynen et al., “External beam radiotherapy and hyperthermia in the treatment of patients with locally advanced prostate carcinoma. Results of long term follow up,” Cancer, vol. 89, pp. 399–403, 2000. View at Google Scholar
  17. G. Calais, M. Alfonsi, E. Bardet et al., “Randomized trial of radiation therapy versus concomitant chemotherapy and radiation therapy for advanced-stage oropharynx carcinoma,” Journal of the National Cancer Institute, vol. 91, no. 24, pp. 2081–2086, 1999. View at Google Scholar
  18. C. A. Perez, M. L. Graham, M. E. Taylor et al., “Management of locally advanced carcinoma of the breast: I. Noninflammatory,” Cancer, vol. 74, no. 1, pp. 453–465, 1994. View at Google Scholar · View at Scopus
  19. C. Perez and L. Bradley, Principles and Practice of Rdiation Oncology, Liponcott, Philadelphia, Pa, USA, 2004.
  20. A. Siglin, “Radiation therapy of prostate cancer,” International Journal of Radiation Oncology, Biology, Physics, vol. 76, pp. 31–35, 2010. View at Google Scholar
  21. M. S. Anscher, T. V. Samulski, R. Dodge, L. R. Prosnitz, and M. W. Dewhirst, “Combined external beam irradiation and external regional hyperthermia for locally advanced adenocarcinoma of the prostate,” International Journal of Radiation Oncology, Biology, Physics, vol. 37, no. 5, pp. 1059–1065, 1997. View at Publisher · View at Google Scholar · View at Scopus
  22. H. I. Bicher and R. S. Wolfstein, “Clinical use of regional hyperthermia,” Advances in Experimental Medicine and Biology, vol. 267, pp. 1–20, 1990. View at Google Scholar · View at Scopus
  23. H. I. Bicher and R. S. Wolfstein, “Local hyperthermia for superficial and moderately deep tumors—factors affecting response,” Advances in Experimental Medicine and Biology, vol. 267, pp. 353–367, 1990. View at Google Scholar · View at Scopus
  24. H. I. Bicher, R. S. Wolfstein, and P. L. Chatham, “Hyperthermic adjunct treatment for specific sites: nasopharynx, pancreas, liver, chest and pelvis. Preliminary experience,” International Journal of Hyperthermia, vol. 3, p. 551, 1987. View at Google Scholar
  25. C. C. Vernon, J. W. Hand, S. B. Field et al., “Radiotherapy with or without hyperthermia in the treatment of superficial localized breast cancer: results from five randomized controlled trials,” International Journal of Radiation Oncology, Biology, Physics, vol. 35, no. 4, pp. 731–744, 1996. View at Publisher · View at Google Scholar · View at Scopus
  26. S. Welz, T. Hehr, U. Lamprecht, H. Scheithauer, W. Budach, and M. Bamberg, “Thermoradiotherapy of the chest wall in locally advanced or recurrent breast cancer with marginal resection,” International Journal of Hyperthermia, vol. 21, no. 2, pp. 159–167, 2005. View at Publisher · View at Google Scholar · View at Scopus