Table of Contents
Conference Papers in Medicine
Volume 2013 (2013), Article ID 910363, 7 pages
http://dx.doi.org/10.1155/2013/910363
Conference Paper

Oncothermia with Chemotherapy in the Patients with Small-Cell Lung Cancer

1Department of Thoracic & Cardio-Vascular Surgery, Gangnam Severance Hospital, College of Medicine, Yonsei University, Seoul 120-752, Republic of Korea
2Department of Diagnostic Radiology, Gangnam Severance Hospital, College of Medicine, Yonsei University, Seoul 120-752, Republic of Korea
3Department of Medical Oncology, Gangnam Severance Hospital, College of Medicine, Yonsei University, Seoul 120-752, Republic of Korea

Received 18 January 2013; Accepted 3 April 2013

Academic Editors: G. Baronzio, M. Jackson, and A. Szasz

This Conference Paper is based on a presentation given by Doo Yun Lee at “Conference of the International Clinical Hyperthermia Society 2012” held from 12 October 2012 to 14 October 2012 in Budapest, Hungary.

Copyright © 2013 Doo Yun Lee et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Small-cell lung cancer (SCLC) is one of the most aggressive and lethal forms of lung cancers. Chemotherapy and radiotherapy would be standard modality for SCLC with median survival being less than 4 months only. Complementary treatment to chemotherapy is desired. Oncothermia will be one of the candidates to this addition. We have made a study of 31 SCLC patients from April 2006 to March 2012. 23 cases were treated with combined chemotherapy and oncothermia, and 8 cases were treated with chemotherapy alone. Three patients from 14 patients (14/31) died in the study period; there were equal numbers in the two arms, including one long survival case of 28 months and one of 26 months, in the combination and chemo-group, respectively .16 patients (16/31) are alive: 4 patients with chemotherapy only, including one long survival case of 28.7 months, and 11 cases with combined therapy including three long survival cases of more than 3 years. We conclude that the combined use of chemotherapy and oncothermia has significantly enhanced the survival rate in comparison with the use of chemotherapy alone (log-rank test: P value < 0.02).