Table of Contents
Conference Papers in Medicine
Volume 2013 (2013), Article ID 953482, 6 pages
http://dx.doi.org/10.1155/2013/953482
Conference Paper

Bystander Effect of Oncothermia

1Department of Veterinary Clinical Medicine, Faculty of Veterinary Science, Tottori University, 4-101 Koyama Minami, Tottori 680-8553, Japan
21st Department of Pathology and Experimental Cancer Research, Semmelweis University, Üllői út 26., 1085 Budapest, Hungary
3“Frederic Joliot Curie” National Research Institute for Radiobiology and Radiohygiene, XXII. Ker. Anna u. 5., 1221 Budapest, Hungary
4Biotechnics Department, Faculty of Engineering, St. István University, Pater K. u. 1., 2100 Godollo, Hungary

Received 17 January 2013; Accepted 28 May 2013

Academic Editors: G. Baronzio, M. Jackson, D. Y. Lee, and A. Szasz

This Conference Paper is based on a presentation given by G. Andocs at “Conference of the International Clinical Hyperthermia Society 2012” held from 12 October 2012 to 14 October 2012 in Budapest, Hungary.

Copyright © 2013 G. Andocs et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Metastatic form of malignant tumor diseases is the most serious problem in oncology and the greatest challenge in tumor therapy. Conventional therapeutical approaches (surgery, irradiation, and chemotherapy) cannot manage this challenge in oncological practice. According to our theory, oncothermia treatment-induced immunogenic tumor cell death can be a very good basis for immunotherapy combination to make systemic tumor control from a local tumor destruction effect. We summarize the molecular basis of the oncothermia treatment-induced immunogenic cell death as a necessary basic condition to achieve the bystander effect.