Research Article

Blood-Brain Barrier Breakdown Following Traumatic Brain Injury: A Possible Role in Posttraumatic Epilepsy

Figure 1

Imaging modalities allow for BBB permeability evaluation and quantification. (a) Control subject: no BBB disruption is observed within the brain parenchyma (areas of significant differences are found in blood vessels, sinuses and the choroid plexus). Increased BBB permeability ( 𝐾 t r a n s ) and extravascular volume ( 𝑣 𝑒 ) are also localized to those same structures. (b) A 28-year-old PTE patient 10 days following TBI. A region of increased BBB permeability is detected over the left parietal lobe in both methods (arrows).
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(a)
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(b)