Emotional Regulation and Depression: A Potential Mediator between Heart and Mind

Table 1

Emotional regulation and depression link in clinical and neuroimaging studies.

Emotional regulation and depression
Clinical studies	Neuroimaging studies
Depressed patients show; (i) inappropriate or ineffective emotion regulation; (ii) difficulties in cognitive control; (iii) difficulties in processing negative material (which leads to greater rumination, less use of reappraisal strategies, and more use of expressive suppression); (iv) negative self-report biases.	Depressed patients show; (i) dysfunctional stress responses; (ii) decrease in mu-opioid receptor binding potential in the left inferior temporal cortex; (iii) abnormal amygdala activation; (iv) dysfunctional ventral prefrontal cortex activation.