Table of Contents
Cardiovascular Psychiatry and Neurology
Volume 2014, Article ID 747293, 6 pages
http://dx.doi.org/10.1155/2014/747293
Research Article

Impact of Identification and Treatment of Depression in Heart Transplant Patients

1Northwestern Memorial Hospital, Feinberg School of Medicine Department of Medicine, 251 E Huron, Northwestern University, Chicago, IL 60616, USA
2Feinberg School of Medicine Department of Psychiatry, Northwestern University, Chicago, IL 60616, USA
3Feinberg School of Medicine Department of Medicine, Division of Cardiology, Northwestern University, Chicago, IL 60616, USA

Received 28 May 2014; Revised 23 August 2014; Accepted 29 August 2014; Published 14 September 2014

Academic Editor: Kate Scott

Copyright © 2014 Ike Okwuosa et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. V. L. Roger, A. S. Go, D. M. Lloyd-Jones et al., “Heart disease and stroke statistics—2011 update,” Circulation, vol. 12, pp. 3:e18–3:e209, 2011. View at Google Scholar
  2. P. A. Heidenreich, J. G. Trogdon, O. A. Khavjou et al., “Forecasting the future of cardiovascular disease in the United States,” Circulation, vol. 123, no. 8, pp. 933–944, 2011. View at Publisher · View at Google Scholar · View at Scopus
  3. T. Rutledge, V. A. Reis, S. E. Linke, B. H. Greenberg, and P. J. Mills, “Depression in heart failure. a meta-analytic review of prevalence, intervention effects, and associations with clinical outcomes,” Journal of the American College of Cardiology, vol. 48, no. 8, pp. 1527–1537, 2006. View at Publisher · View at Google Scholar · View at Scopus
  4. R. Norwood, “Prevalence and impact of depression in chronic obstructive pulmonary disease patients,” Current Opinion in Pulmonary Medicine, vol. 12, no. 2, pp. 113–117, 2006. View at Publisher · View at Google Scholar · View at Scopus
  5. L. E. Egede, “Effect of comorbid chronic diseases on prevalence and odds of depression in adults with diabetes,” Psychosomatic Medicine, vol. 67, no. 1, pp. 46–51, 2005. View at Publisher · View at Google Scholar · View at Scopus
  6. “Current depression among adults—United States, 2006 and 2008,” The Journal of the American Medical Association, vol. 304, pp. 2233–2235, 2010.
  7. J. Butler, N. S. McCoin, I. D. Feurer et al., “Modeling the effects of functional performance and post-transplant comorbidities on health-related quality of life after heart transplantation,” Journal of Heart and Lung Transplantation, vol. 22, no. 10, pp. 1149–1156, 2003. View at Publisher · View at Google Scholar · View at Scopus
  8. L. Petrucci, S. Ricotti, I. Michelini et al., “Return to work after thoracic organ transplantation in a clinically-stable population,” European Journal of Heart Failure, vol. 9, no. 11, pp. 1112–1119, 2007. View at Publisher · View at Google Scholar · View at Scopus
  9. M. A. Dew, R. L. Kormos, A. F. DiMartini et al., “Prevalence and risk of depression and anxiety-related disorders during the first three years after heart transplantation,” Psychosomatics, vol. 42, no. 4, pp. 300–313, 2001. View at Publisher · View at Google Scholar · View at Scopus
  10. F. Dobbels, S. De Geest, S. Martin, J. Van Cleemput, W. Droogne, and J. Vanhaecke, “Prevalence and correlates of depression symptoms at 10 years after heart transplantation: Continuous attention required,” Transplant International, vol. 17, no. 8, pp. 424–431, 2004. View at Publisher · View at Google Scholar · View at Scopus
  11. W. F. Stewart, J. A. Ricci, E. Chee, S. R. Hahn, and D. Morganstein, “Cost of lost productive work time among US workers with depression,” The Journal of the American Medical Association, vol. 289, no. 23, pp. 3135–3144, 2003. View at Publisher · View at Google Scholar · View at Scopus
  12. M. L. Chung, T. A. Lennie, R. L. Dekker, J. R. Wu, and D. K. Moser, “Depressive symptoms and poor social support have a synergistic effect on event-free survival in patients with heart failure,” Heart and Lung, vol. 40, no. 6, pp. 492–501, 2011. View at Publisher · View at Google Scholar · View at Scopus
  13. J. Jünger, D. Schellberg, T. Müller-Tasch et al., “Depression increasingly predicts mortality in the course of congestive heart failure,” European Journal of Heart Failure, vol. 7, no. 2, pp. 261–267, 2005. View at Publisher · View at Google Scholar · View at Scopus
  14. D. J. Kupfer, E. Frank, and J. M. Perel, “The advantage of early treatment intervention in recurrent depression,” Archives of General Psychiatry, vol. 46, no. 9, pp. 771–775, 1989. View at Publisher · View at Google Scholar · View at Scopus
  15. J. C. Fournier, R. J. DeRubeis, S. D. Hollon et al., “Antidepressant drug effects and depression severity: a patient-level meta-analysis,” JAMA - Journal of the American Medical Association, vol. 303, no. 1, pp. 47–53, 2010. View at Publisher · View at Google Scholar · View at Scopus
  16. B. Campbell and G. Etringer, “Posttransplant quality of life issues: depression-related noncompliance in cardiac transplant patients,” Transplantation Proceedings, vol. 31, no. 4, pp. 59S–60S, 1999. View at Publisher · View at Google Scholar · View at Scopus
  17. D. C. Fisher, K. D. Lake, T. J. Reutzel, and R. W. Emery, “Changes in health-related quality of life and depression in heart transplant recipients,” Journal of Heart and Lung Transplantation, vol. 14, no. 2, pp. 373–381, 1995. View at Google Scholar · View at Scopus
  18. P. Fusar-Poli, V. Martinelli, C. Klersy et al., “Depression and quality of life in patients living 10 to 18 years beyond heart transplantation,” Journal of Heart and Lung Transplantation, vol. 24, no. 12, pp. 2269–2278, 2005. View at Publisher · View at Google Scholar · View at Scopus
  19. E. W. Ruzyczka, I. Milaniak, P. Przybyłowski et al., “Depression and quality of life in terms of personal resources in heart transplant recipients,” Transplantation Proceedings, vol. 43, no. 8, pp. 3076–3081, 2011. View at Publisher · View at Google Scholar · View at Scopus
  20. H. Spaderna, D. Zahn, S. Schulze Schleithoff et al., “Depression and disease severity as correlates of everyday physical activity in heart transplant candidates,” Transplant International, vol. 23, no. 8, pp. 813–822, 2010. View at Publisher · View at Google Scholar · View at Scopus
  21. M. Billingham and J. A. Kobashigawa, “The revised ISHLT heart biopsy grading scale,” Journal of Heart and Lung Transplantation, vol. 24, no. 11, p. 1709, 2005. View at Publisher · View at Google Scholar · View at Scopus
  22. R. Schulz, S. R. Beach, D. G. Ives, L. M. Martire, A. A. Ariyo, and W. J. Kop, “Association between depression and mortality in older adults: the cardiovascular health study,” Archives of Internal Medicine, vol. 160, no. 12, pp. 1761–1768, 2000. View at Publisher · View at Google Scholar · View at Scopus
  23. R. M. Carney and K. E. Freedland, “Depression, mortality, and medical morbidity in patients with coronary heart disease,” Biological Psychiatry, vol. 54, no. 3, pp. 241–247, 2003. View at Publisher · View at Google Scholar · View at Scopus
  24. J. C. Barefoot and M. Schroll, “Symptoms of depression, acute myocardial infarction, and total mortality in a community sample,” Circulation, vol. 93, no. 11, pp. 1976–1980, 1996. View at Publisher · View at Google Scholar · View at Scopus
  25. B. W. J. H. Penninx, A. T. F. Beekman, A. Honig et al., “Depression and cardiac mortality: results from a community-based longitudinal study,” Archives of General Psychiatry, vol. 58, no. 3, pp. 221–227, 2001. View at Publisher · View at Google Scholar · View at Scopus
  26. S. Zipfel, A. Schneider, B. Wild et al., “Effect of depressive symptoms on survival after heart transplantation,” Psychosomatic Medicine, vol. 64, no. 5, pp. 740–747, 2002. View at Publisher · View at Google Scholar · View at Scopus
  27. D. E. Bush, R. C. Ziegelstein, M. Tayback et al., “Even minimal symptoms of depression increase mortality risk after acute myocardial infarction,” The American Journal of Cardiology, vol. 88, no. 4, pp. 337–341, 2001. View at Publisher · View at Google Scholar · View at Scopus
  28. O. E. Havik, B. Sivertsen, A. Relbo et al., “Depressive symptoms and all-cause mortality after heart transplantation,” Transplantation, vol. 84, no. 1, pp. 97–103, 2007. View at Publisher · View at Google Scholar · View at Scopus
  29. R. M. Carney, K. E. Freedland, S. A. Eisen, M. W. Rich, and A. S. Jaffe, “Major depression and medication adherence in elderly patients with coronary artery disease,” Health Psychology, vol. 14, no. 1, pp. 88–90, 1995. View at Publisher · View at Google Scholar · View at Scopus
  30. M. R. DiMatteo, H. S. Lepper, and T. W. Croghan, “Depression is a risk factor for noncompliance with medical treatment meta-analysis of the effects of anxiety and depression on patient adherence,” Archives of Internal Medicine, vol. 160, no. 14, pp. 2101–2107, 2000. View at Publisher · View at Google Scholar · View at Scopus
  31. D. Cukor, D. S. Rosenthal, R. M. Jindal, C. D. Brown, and P. L. Kimmel, “Depression is an important contributor to low medication adherence in hemodialyzed patients and transplant recipients,” Kidney International, vol. 75, no. 11, pp. 1223–1229, 2009. View at Publisher · View at Google Scholar · View at Scopus
  32. A. Gehi, D. Haas, S. Pipkin, and M. A. Whooley, “Depression and medication adherence in outpatients with coronary heart disease: findings from the heart and soul study,” Archives of Internal Medicine, vol. 165, no. 21, pp. 2508–2513, 2005. View at Publisher · View at Google Scholar · View at Scopus
  33. M. A. Dew, L. H. Roth, H. C. Schulberg et al., “Prevalence and predictors of depression and anxiety-related disorders during the year after heart transplantation,” General Hospital Psychiatry, vol. 18, pp. 48S–61S, 1996. View at Google Scholar · View at Scopus
  34. F. Dobbels, J. Vanhaecke, L. Dupont et al., “Pretransplant predictors of posttransplant adherence and clinical outcome: an evidence base for pretransplant psychosocial screening,” Transplantation, vol. 87, no. 10, pp. 1497–1504, 2009. View at Publisher · View at Google Scholar · View at Scopus
  35. J. E. Owen, C. L. Bonds, and D. K. Wellisch, “Psychiatric evaluations of heart transplant candidates: Predicting post-transplant hospitalizations, rejection episodes, and survival,” Psychosomatics, vol. 47, no. 3, pp. 213–222, 2006. View at Publisher · View at Google Scholar · View at Scopus
  36. S. S. Rogal, D. Landsittel, O. Surman, R. T. Chung, and A. Rutherford, “Pretransplant depression, antidepressant use, and outcomes of orthotopic liver transplantation,” Liver Transplantation, vol. 17, no. 3, pp. 251–260, 2011. View at Publisher · View at Google Scholar · View at Scopus
  37. L. Eisenberg, “Treating depression and anxiety in primary care: closing the gap between knowledge and practice,” The New England Journal of Medicine, vol. 326, no. 16, pp. 1080–1084, 1992. View at Publisher · View at Google Scholar · View at Scopus
  38. S. Moussavi, S. Chatterji, E. Verdes, A. Tandon, V. Patel, and B. Ustun, “Depression, chronic diseases, and decrements in health: results from the World Health Surveys,” The Lancet, vol. 370, no. 9590, pp. 851–858, 2007. View at Publisher · View at Google Scholar · View at Scopus
  39. L. F. Berkman, J. Blumenthal, M. Burg et al., “Effects of treating depression and low perceived social support on clinical events after myocardial infarction: the Enhancing Recovery in Coronary Heart Disease Patients (ENRICHD) randomized trial,” The Journal of the American Medical Association, vol. 289, no. 23, pp. 3106–3116, 2003. View at Publisher · View at Google Scholar · View at Scopus
  40. M. R. Costanzo, A. Dipchand, R. Starling et al., “The international society of heart and lung transplantation guidelines for the care of heart transplant recipients,” Journal of Heart and Lung Transplantation, vol. 29, no. 8, pp. 914–956, 2010. View at Publisher · View at Google Scholar · View at Scopus
  41. P. Fusar-Poli, M. Picchioni, V. Martinelli et al., “Anti-depressive Therapies After Heart Transplantation,” Journal of Heart and Lung Transplantation, vol. 25, no. 7, pp. 785–793, 2006. View at Publisher · View at Google Scholar · View at Scopus
  42. K. Kroenke, R. L. Spitzer, and J. B. W. Williams, “The PHQ-9: validity of a brief depression severity measure,” Journal of General Internal Medicine, vol. 16, no. 9, pp. 606–613, 2001. View at Publisher · View at Google Scholar · View at Scopus
  43. L. S. Williams, E. J. Brizendine, L. Plue et al., “Performance of the PHQ-9 as a screening tool for depression after stroke,” Stroke, vol. 36, no. 3, pp. 635–638, 2005. View at Publisher · View at Google Scholar · View at Scopus
  44. B. Löwe, I. Schenkel, C. Carney-Doebbeling, and C. Göbel, “Responsiveness of the PHQ-9 to psychopharmacological depression treatment,” Psychosomatics, vol. 47, no. 1, pp. 62–67, 2006. View at Publisher · View at Google Scholar · View at Scopus
  45. A. Pinto-Meza, A. Serrano-Blanco, M. T. Peñarrubia, E. Blanco, and J. M. Haro, “Assessing depression in primary care with the PHQ-9: can it be carried out over the telephone?” Journal of General Internal Medicine, vol. 20, no. 8, pp. 738–742, 2005. View at Publisher · View at Google Scholar · View at Scopus
  46. P. L. DiGiorgi, M. S. Reel, B. Thornton, E. Burton, Y. Naka, and M. C. Oz, “Heart transplant and left ventricular assist device costs,” Journal of Heart and Lung Transplantation, vol. 24, no. 2, pp. 200–204, 2005. View at Publisher · View at Google Scholar · View at Scopus
  47. T. I. Shireman, J. E. Martin, and J. F. Whiting, “The cost of transplant graft maintenance following solid organ transplantation,” Transplantation Proceedings, vol. 33, no. 1-2, pp. 1920–1921, 2001. View at Publisher · View at Google Scholar · View at Scopus
  48. M. E. Lacruz, R. T. Emeny, S. Haefner et al., “Relation between depressed mood, somatic comorbidities and health service utilisation in older adults: results from the KORA-Age study,” Age and Ageing, vol. 41, no. 2, pp. 183–190, 2012. View at Publisher · View at Google Scholar · View at Scopus
  49. V. Myers, Y. Gerber, Y. Benyamini, U. Goldbourt, and Y. Drory, “Post-myocardial infarction depression: increased hospital admissions and reduced adoption of secondary prevention measures—a longitudinal study,” Journal of Psychosomatic Research, vol. 72, no. 1, pp. 5–10, 2012. View at Publisher · View at Google Scholar · View at Scopus
  50. R. L. Reese, K. E. Freedland, B. C. Steinmeyer, M. W. Rich, J. W. Rackley, and R. M. Carney, “Depression and rehospitalization following acute myocardial infarction,” Circulation: Cardiovascular Quality and Outcomes, vol. 4, no. 6, pp. 626–633, 2011. View at Publisher · View at Google Scholar · View at Scopus
  51. G. Bruschi, T. Colombo, F. Oliva et al., “Heart transplantation: 25 years' single-centre experience,” Journal of Cardiovascular Medicine, vol. 14, no. 9, pp. 637–647, 2013. View at Publisher · View at Google Scholar