Validated Stability Indicating HPTLC Method for the Determination of Dutasteride in Pharmaceutical Dosage Forms

Table 1

Summary of validation parameters of proposed HPTLC method.

Parameters	Value
Linearity and range	200–3000 ng/spot
Correlation coefficient (𝑟^2)	0.9989
Limit of detection	10 ng/spot
Limit of quantification	50 ng/spot
% accuracy ± SD^a (𝑛=3)	99.81%  ± 0.697
Precision (% RSD^b)
Repeatability of sample application (𝑛=6)	0.53%
Repeatability of sample measurement (𝑛=6)	0.39%
Intraday (𝑛=3)	0.684%–1.048%
Interday (𝑛=3)	1.012%–1.224%
Robustness	Robust
Specificity	Specific
% assay ± SD^a	99.49%  ± 0.56

^aStandard deviation; ^brelative standard deviation.