Table of Contents
Chromatography Research International
Volume 2011 (2011), Article ID 482308, 6 pages
http://dx.doi.org/10.4061/2011/482308
Research Article

Analysis of Chloramphenicol and Its Related Compound 2-Amino-1-(4-nitrophenyl)propane-1,3-diol by Reversed-Phase High-Performance Liquid Chromatography with UV Detection

1Faculty of Science and Technology, Al-Quds University, P.O. Box 20002, East Jerusalem, Palestine
2Research and Development Department, Jerusalem Pharmaceutical Co., P.O. Box 3570, Al-Bireh, Palestine

Received 18 May 2011; Revised 9 July 2011; Accepted 10 July 2011

Academic Editor: Wenkui Li

Copyright © 2011 Fuad Al-Rimawi and Maher Kharoaf. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. G. Vigh and J. Inczédy, “Separation of some chloramphenicol intermediates by high-pressure liquid chromatography,” Journal of Chromatography, vol. 116, no. 2, pp. 472–474, 1976. View at Google Scholar · View at Scopus
  2. M. J. LeBelle, D. C. Young, K. C. Graham, and W. L. Wilson, “High-performance liquid chromatographic determination of chloramphenicol and 1-(4'-nitrophenyl)-2-aminopropane-1,3-diol in pharmaceutical formulations,” Journal of Chromatography, vol. 170, no. 1, pp. 282–287, 1979. View at Google Scholar · View at Scopus
  3. B. Wiese, K. Martin, and J. Hermansson, “Determination of chloramphenicol and its monosuccinate ester in piglet plasma using HPLC,” Chromatographia, vol. 15, no. 12, pp. 737–742. View at Publisher · View at Google Scholar
  4. Y. Boer and A. Pijnenburg, “HPLC determination of chloramphenicol degradation in eye drops,” Pharmacy World & Science, vol. 5, no. 3, pp. 95–101, 1983. View at Google Scholar
  5. S. Seth and N. R. Bannerjee, “Estimation of chloramphenicol in presence of its degradation products,” Indian Journal of Pharmaceutical Sciences, vol. 49, no. 2, pp. 58–60, 1987. View at Google Scholar · View at Scopus
  6. G. S. Sadana and A. B. Ghogare, “Simultaneous determination of chloramphenicol and benzocaine in topical formulations by high-performance liquid chromatography,” Journal of Chromatography, vol. 542, no. 2, pp. 515–520, 1991. View at Google Scholar · View at Scopus
  7. L. Hong and H. Altorfer, “Determination of assay and impurities of gamma irradiated chloramphenicol in eye ointment,” Journal of Pharmaceutical and Biomedical Analysis, vol. 24, no. 4, pp. 667–674, 2001. View at Publisher · View at Google Scholar · View at Scopus
  8. M. J. Bogusz, H. Hassan, E. Al-Enazi, Z. Ibrahim, and M. Al-Tufail, “Rapid determination of chloramphenicol and its glucuronide in food products by liquid chromatography–electrospray negative ionization tandem mass spectrometry,” Journal of Chromatogr B, vol. 807, no. 2, pp. 343–356, 2004. View at Google Scholar
  9. D. Visky, E. Haghedooren, P. Dehouck et al., “Facilitated column selection in pharmaceutical analyses using a simple column classification system,” Journal of Chromatography A, vol. 1101, no. 1-2, pp. 103–114, 2006. View at Publisher · View at Google Scholar · View at Scopus
  10. S. L. Ali, “Separation and determination of the hydrolysis products of chloramphenicol in pharmaceutical preparations by high-performance liquid chromatography,” Journal of Chromatography, vol. 154, no. 1, pp. 103–105, 1978. View at Google Scholar · View at Scopus
  11. United States Pharmacopoeia—National Formulary 26, vol. 31, Rockville, MD, USA, 2008.
  12. British Pharmacopoeia Commission, British Pharmacopoeia, London, UK, 2007.
  13. “Stability testing of new active substances and medicinal products,” ICH Topic Q1A. ICH Harmonized Tripartite Guidelines, ICH, Surrey, UK, CPMP/ICH/280/95, 1996.
  14. United States Pharmacopoeia, National Formulary, Validation of Compendial Methods, chapter 1225, United States Pharmacopoeia, Rockville, Md, USA, 2007.
  15. “Validation of analytical procedures-PA/PH/OMCL (05) 47 DEF,” in Proceedings of the International Conference on Harmonization (ICH), OMCL Network/EDQM of the Council of Europe, June 2005.
  16. J. Mark Green, “A practical guide to analytical method validation,” Analytical Chemistry, pp. 305A–309A, 1996. View at Google Scholar · View at Scopus
  17. L. Huber, “Validation of analytical methods,” in Validation and Qualification in the Analytical Laboratories, L. Huber, Ed., p. 107, Interpharm Press, Buffalo Grove. Ill, USA, 1998. View at Google Scholar