Table of Contents
Chromatography Research International
Volume 2011 (2011), Article ID 957508, 11 pages
http://dx.doi.org/10.4061/2011/957508
Review Article

Liquid Chromatographic Investigation of Spontaneous Oscillatory In Vitro Chiral Conversion and Spontaneous Oscillatory Condensation of Simple Carboxylic Acids in Aqueous and Nonaqueous Media

Institute of Chemistry, University of Silesia, 9 Szkolna Street, 40-006 Katowice, Poland

Received 16 August 2010; Accepted 30 September 2010

Academic Editor: Irene Panderi

Copyright © 2011 Mieczyslaw Sajewicz and Teresa Kowalska. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Oscillatory reactions are a narrow reaction type among the entity of chemical reactions and those involving purely organic compounds make a small contribution to an overall number of all known oscillatory reactions. The most abundant type is purely inorganic and mixed inorganic-organic oxidation-reduction reactions, basically because monitoring them is relatively easy (e.g., with use of potentiometric measurements). Investigation of the organic reactions can be more demanding, and then chromatography is an analytical technique of choice. In this paper, we provide an overview of chromatographic evidence with oscillatory reactions discovered in our laboratory in the course of the last several years that involve the low-molecular-weight carboxylic acids (profen drugs, amino acids, and hydroxy acids). The investigated processes comprise the oscillatory chiral conversion and the oscillatory condensation, spontaneously running in the aqueous and nonaqueous abiotic media, and they were traced with use of TLC and HPLC coupled with different detector types.