Chromatography Research International / 2012 / Article / Tab 1

Research Article

Development and Validation of a Stability Indicating LC Method for the Assay and Related Substances Determination of a Proteasome Inhibitor Bortezomib

Table 1

Factors and level studied for robustness testing.

Factors Level
−1 0 + 1

(A)  Flow rate (mL/min) 0.8
(B)  Acetonitrile (%) 28.0
(C)  Methanol (%) 79.0 80.0 81.0

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