Table of Contents
Chromatography Research International
Volume 2012, Article ID 851792, 12 pages
Research Article

Quality Control Methodology and Their Application in Analysis on HPLC Fingerprint Spectra of Herbal Medicines

1School of Chemistry and Chemical Engineering of Shandong University, Shandong, Jinan 250100, China
2Department of Chemistry and Chemical Engineering, Shandong Institute of Education, Shandong, Jinan 250100, China
3Medicinal and Pharmaceutical Chemistry Department, National Research Centre, Dokki, Cairo 12311, Egypt

Received 25 June 2011; Revised 25 July 2011; Accepted 25 July 2011

Academic Editor: Teresa Kowalska

Copyright © 2012 Zou Hua-Bin et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


As traditional Chinese medicine (TCM) is gradually accepted by many countries, people pay much attention to the quality of herbal medicines. Because of the significant variation in active components in them, the quality control of herbal medicines is a very important issue. Nowadays, high-performance liquid chromatography (HPLC) fingerprint spectra (FPS) are widely used in identification and quality control of herbal medicines. This paper will analyze the methodology and their application in identifying and evaluating herbal medicines by means of HPLC FPS, which includes simple comparing, clustering, principal component analysis (PCA), and similarity analysis methods.