A New Validated Stability Indicating RP-HPLC Method for Simultaneous Estimation of Pyridoxine Hydrochloride and Meclizine Hydrochloride in Pharmaceutical Solid Dosage Forms

Table 7

Ruggedness of the method.

Amount of PYH (mg tab^−1)	Amount of MEH (mg tab^−1)	Analyst 1, instrument 1, column 1		Analyst 2, instrument 2, column 2
		Amount found PYH (mg tab^−1) (Mean ±  %RSD)*	Amount found MEH (mg tab^−1) (Mean ±  %RSD)*	Amount found PYH (mg tab^−1) (Mean ±  %RSD)*	Amount found MEH (mg tab^−1) (Mean ±  %RSD)*
50	25	50.53 ± 0.3	25.63 ± 0.3	50.97 ± 0.04	25.60 ± 0.50

∗Mean of six replicates.