Stability Study of Darunavir Ethanolate Tablets Applying a New Stability-Indicating HPLC Method

Table 2

Validation parameters for chromatographic method.

Parameters	Chromatographic method
Useful concentration, µg/mL	15
Analytical curve	43272.84𝑋 + 6875.41
Determination coefficient (𝑟^2)	0.997
RSD of repeatability^a (%, 𝑛 = 18)	1.75
RSD intermediate precision (%, 𝑛 = 12)	3.28
Accuracy (%)	99.64
RSD of accuracy^a (%, 𝑛 = 18)	1.36
Detection limit^b, µg/mL	0.87
Quantitation limit^c, µg/mL	2.89

^aMeasured at the six concentration levels; ^b3 𝜎/𝑆; ^c10 𝜎/𝑆.