Table of Contents
Chromatography Research International
Volume 2014, Article ID 521697, 7 pages
http://dx.doi.org/10.1155/2014/521697
Research Article

High-Performance Liquid Chromatography Determination of Meloxicam and Piroxicam with Ultraviolet Detection

1Department of Biomedical and Diagnostic Sciences, College of Veterinary Medicine, University of Tennessee, 2407 River Drive, Knoxville, TN 37996, USA
2Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Tennessee, 2407 River Drive, Knoxville, TN 37996, USA

Received 19 August 2014; Revised 25 September 2014; Accepted 25 September 2014; Published 27 October 2014

Academic Editor: Teresa Kowalska

Copyright © 2014 Sherry Cox et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. A. J. Kreuder, J. F. Coetzee, L. W. Wulf et al., “Bioavailability and pharmacokinetics of oral meloxicam in llamas,” BMC Veterinary Research, vol. 8, article 85, 2012. View at Publisher · View at Google Scholar · View at Scopus
  2. P. R. Malreddy, J. F. Coetzee, B. Kukanich, and R. Gehring, “Pharmacokinetics and milk secretion of gabapentin and meloxicam co-administered orally in Holstein-Friesian cows,” Journal of Veterinary Pharmacology and Therapeutics, vol. 36, no. 1, pp. 14–20, 2013. View at Publisher · View at Google Scholar · View at Scopus
  3. J.-W. Bae, C.-I. Choi, C.-G. Jang, and S.-Y. Lee, “Effects of CYP2C9*1/*13 on the pharmacokinetics and pharmacodynamics of meloxicam,” British Journal of Clinical Pharmacology, vol. 71, no. 4, pp. 550–555, 2011. View at Publisher · View at Google Scholar · View at Scopus
  4. H. Zhang and H.-K. Choi, “Analysis of meloxicam by high-performance liquid chromatography with cloud-point extraction,” Analytical and Bioanalytical Chemistry, vol. 392, no. 5, pp. 947–953, 2008. View at Publisher · View at Google Scholar · View at Scopus
  5. J.-W. Bae, M.-J. Kim, C.-G. Jang, and S.-Y. Lee, “Determination of meloxicam in human plasma using a HPLC method with UV detection and its application to a pharmacokinetic study,” Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, vol. 859, no. 1, pp. 69–73, 2007. View at Publisher · View at Google Scholar · View at Scopus
  6. A. Medvedovici, F. Albu, C. Georgita, C. Mircioiu, and V. David, “A non-extracting procedure for the determination of meloxicam in plasma samples by HPLC-DIODE Array Detection,” Arzneimittel-Forschung, vol. 55, no. 6, pp. 326–331, 2005. View at Google Scholar · View at Scopus
  7. H. Blain, C. Boileau, F. Lapicque et al., “Limitation of the in vitro whole blood assay for predicting the COX selectivity of NSAIDs in clinical use,” British Journal of Clinical Pharmacology, vol. 53, no. 3, pp. 255–265, 2002. View at Publisher · View at Google Scholar · View at Scopus
  8. D. Turck, U. Busch, G. Heinzel, and H. Narjes, “Clinical pharmacokinetics of meloxicam,” Arzneimittel Forschung-Drug Research, vol. 47, no. 3, pp. 253–258, 1997. View at Google Scholar
  9. J. Schmid, U. Busch, G. Heinzel, G. Bozler, S. Kaschke, and M. Kummer, “Pharmacokinetics and metabolic pattern after intravenous infusion and oral administration to healthy subjects,” Drug Metabolism and Disposition, vol. 23, no. 11, pp. 1206–1214, 1995. View at Google Scholar · View at Scopus
  10. J. L. Wiesner, A. D. de Jager, F. C. W. Sutherland et al., “Sensitive and rapid liquid chromatography-tandem mass spectrometry method for the determination of meloxicam in human plasma,” Journal of Chromatography B, vol. 785, no. 1, pp. 115–121, 2003. View at Publisher · View at Google Scholar · View at Scopus
  11. P.-L. Toutain, N. Reymond, V. Laroute et al., “Pharmacokinetics of meloxicam in plasma and urine of horses,” American Journal of Veterinary Research, vol. 65, no. 11, pp. 1542–1547, 2004. View at Publisher · View at Google Scholar · View at Scopus
  12. H.-K. Han and H.-K. Choi, “Improved absorption of meloxicam via salt formation with ethanolamines,” European Journal of Pharmaceutics and Biopharmaceutics, vol. 65, no. 1, pp. 99–103, 2007. View at Publisher · View at Google Scholar · View at Scopus
  13. B. Dasandi, H. Saroj, and K. M. Bhat, “LC determination and pharmacokinetics of meloxicam,” Journal of Pharmaceutical and Biomedical Analysis, vol. 28, no. 5, pp. 999–1004, 2002. View at Publisher · View at Google Scholar · View at Scopus
  14. H. Modesto Rigato, G. Duarte Mendes, N. Carter do Carmo Borges, and R. A. Moreno, “Meloxicam determination in human plasma by high-performance liquid chromatography coupled with tandem mass spectrometry (LC-MS-MS) in Brazilian bioequivalence studies,” International Journal of Clinical Pharmacology and Therapeutics, vol. 44, no. 10, pp. 489–498, 2006. View at Publisher · View at Google Scholar · View at Scopus
  15. W. R. G. Baeyens, G. van der Weken, E. D'haeninck et al., “Application of an alkyl-diol silica precolumn in a column-switching system for the determination of meloxicam in plasma,” Journal of Pharmaceutical and Biomedical Analysis, vol. 32, no. 4-5, pp. 839–846, 2003. View at Publisher · View at Google Scholar · View at Scopus
  16. K. Baert and P. de Backer, “Disposition of sodium salicylate, flunixin and meloxicam after intravenous administration in broiler chickens,” Journal of Veterinary Pharmacology and Therapeutics, vol. 25, no. 6, pp. 449–453, 2002. View at Publisher · View at Google Scholar · View at Scopus
  17. J. A. Palma-Aguirre, M. Lopez-Gamboa, L. Cariño, V. Burke-Fraga, and M. González-de la Parra, “Relative bioavailability of two oral formulations of piroxicam 20 mg: a single-dose, randomized-sequence, open-label, two-period crossover comparison in healthy Mexican adult volunteers,” Clinical Therapeutics, vol. 32, no. 2, pp. 357–364, 2010. View at Publisher · View at Google Scholar · View at Scopus
  18. L. Edno, F. Bressolle, B. Combe, and M. Galtier, “A reproducible and rapid HPLC assay for quantitation of piroxicam in plasma,” Journal of Pharmaceutical and Biomedical Analysis, vol. 13, no. 6, pp. 785–789, 1995. View at Publisher · View at Google Scholar · View at Scopus
  19. M. T. Maya, J. P. Pais, and J. Morais, “A rapid method for the determination of piroxicam in plasma by high-performance liquid chromatography,” Journal of Pharmaceutical and Biomedical Analysis, vol. 13, no. 3, pp. 319–322, 1995. View at Publisher · View at Google Scholar · View at Scopus