A Validated Stability Indicating RP-HPLC Method Development and Validation for Simultaneous Estimation of Aliskiren Hemifumarate and Amlodipine Besylate in Pharmaceutical Dosage Form

Table 5

Results of robustness.

S. number	Parameters	Aliskiren			Amlodipine
		RT	USPC	TF	RT	USPC	TF
1	Flow rate 0.8 mL	4.38	3926	1.29	5.58	4912	1.18
	Flow rate 1.2 mL	3.68	3581	1.23	4.68	4441	1.15
2	Temperature 25°C	3.83	3675	1.26	4.81	4446	1.15
	Temperature 35°C	3.93	3923	1.29	4.81	4821	1.18
3	Mobile phase (−5%)	3.47	3205	1.17	4.36	3668	1.05
	Mobile phase (+5%)	4.40	3625	1.21	5.61	4322	1.09

PA: peak area; RT: retention time (min); USPC-USP plate count; TF: tailing factor.