Research Article

Development and Validation of a Rapid Chemometrics Assisted RP-HPLC with PDA Detection Method for the Simultaneous Estimation of Pyridoxine HCl and Doxylamine Succinate in Bulk and Pharmaceutical Dosage Form

Table 4

The comparison of observed and predicted values under optimum condition.

Optimum conditionResponseExperimental valuePredicted value% error
FactorCondition

Methanol49.37%
Flow rate1 mLtR23.9593.76575.14
Buffer molarity45.14 mMRs210.92110.4734.10