Research Article

Development and Validation of Stability-Indicating RP-UPLC Method for Simultaneous Determination of Related Substances of S(−)Amlodipine and S(−)Metoprolol Succinate in Fixed Dose Combination Tablet Dosage Form

Table 1

Gradient programme of mobile phase.

Time in minuteFlow rate mL/min% of mobile phase-A% of mobile phase-B

0.00.59010
7.00.57030
12.00.55050
13.10.59010
15.00.59010