Development and Validation of Stability-Indicating RP-UPLC Method for Simultaneous Determination of Related Substances of S(−)Amlodipine and S(−)Metoprolol Succinate in Fixed Dose Combination Tablet Dosage Form

Table 6

Results of LOQ precision.

Analyte	%RSD of six injections	value
S(−)Metoprolol	1.06	55
S(−)Amlodipine	1.78	24
Metoprolol Succinamide impurity	0.64	119
Amlodipine related compound-A	0.69	67