Research Article

Validated Stability Indicating Chromatographic Method for the Simultaneous Estimation of Camylofin with NSAID Drugs and a New Approach of Method Transfer from Classical HPLC to a Modern UPLC Instrument

Table 1

Total degradation % of CMF and DCF.

Sr. no.Degradation condition Total degradation %
CMFDCF

1Alkaline (0.1 N NaOH, 0 h)19.334.46
2Oxidative (3% H2O2, 7 h)32.727.04
3Thermal (80°C, 3 h)40.124.03
4Photolytic (Day light, 3 h)21.93 0.5
5Acidic (0.005 N HCl, 0 h)45.2392.59