Development and Validation of New RP-HPLC Method for Simultaneous Determination of Methyl and Propyl Parabens with Levetiracetam in Pure Form and Pharmaceutical Formulation

Table 3

Method precision (% repeatability) of the proposed HPLC method for determination of 6 replicates of LTC, MHB, and PHB.

Levetiracetam			Methyl paraben			Propyl paraben
Nominal conc.	Retention time	Peak area	Nominal conc.	Retention time	Peak area	Nominal conc.	Retention time	Peak area
1 mgmL^−1			20 µgmL^−1			2 µgmL^−1
Mean	1.56	246898		5.66	426905.7		7.850	72556.5
SD	0.004	2603.45		0.015	1263.981		0.00527	392.088
RSD	0.242	1.054		0.269	0.296		0.067	0.540