Case Report

Management of a Parturient with Mast Cell Activation Syndrome: An Anesthesiologist’s Experience

Table 3

Proposed diagnostic criteria for MCAS.

(1) Episodic symptoms of mast cell mediator release involving ≥2 organ systems
(2) Appropriate response to antimediator therapy
(3) Documented increase in validated systemic markers of mast cell activation during episode (e.g., serum tryptase or urinary markers such as histamine metabolites, prostaglandin D2 or its metabolite, and leukotriene E4)
(4) Primary and secondary causes ruled out