Case Report

Break the Spasm with Succinylcholine, but Risk Intraoperative Awareness with Undiagnosed Pseudocholinesterase Deficiency

Table 2

Timeline.

TimeEvent

09: 35IV induction with 200 mg propofol, 50 mg rocuronium, and 100 mcg fentanyl
09: 39Intubation
09: 54Procedure start
10: 34Procedure end, 4/4 twitches on TOF monitoring after reversal with sugammadex
10: 35Emergence
10: 40Extubation; laryngospasm; 40 mg IV succinylcholine administered
10: 50No spontaneous respiratory effort; blood pressure increased from 100/57 to 175/22 and heart rate from 64 to 127; 0/4 twitches on recheck of TOF
10: 51Midazolam 2 mg and propofol 100 mg IV administered; the patient was reintubated and started on a propofol drip
11: 33Transport to PACU intubated and sedated
11: 40Labs for dibucaine number and plasma cholinesterase sent
13: 304/4 twitches on TOF monitor, sedation weaned, patient extubated once awake and following commands
16: 05Patient reports well-controlled pain and no awareness of perioperative events