Case Report

Respiratory Syncytial Virus Pneumonia Treated with Lower-Dose Palivizumab in a Heart Transplant Recipient

Table 2

Common treatments for RSV respiratory tract infection.

DrugDosageFrequency

Ribavirin
 Aerosolized2 gEvery 8 hours for 15 total doses
 Oral / IV*15–20 mg/kgDivided in 3 doses over 10 days
Corticosteroids
 Solu-Medrol10–15 mg/kg/dayOver 3 days
IVIG0.5 g/kgOnce
Palivizumab15 mg/kgOnce
Motavizumab3–15 mg/kgOnce

RSV: respiratory syncytial virus, IVIG: intravenous immunoglobulin.
* IV ribavirin with oral corticosteroids is well tolerated and effective with a lower price than aerosolized ribavirin [20].
There is no consensus as to the appropriate regimen. Steroid selection and dosing are usually center dependent.
Motavizumab is a new, potent anti-RSV immunoglobulin, recently not approved by the FDA in a recent filing for licensure [21].