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Case Reports in Cardiology
Volume 2013, Article ID 704859, 3 pages
Case Report

Brugada Pattern Electrocardiogram Unmasked with Cocaine Ingestion

1Department of Hospital Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, 9500 Euclid Avenue, Mail Code A13, Cleveland, OH 44195, USA
2Department of Internal Medicine, Cleveland Clinic, Cleveland, OH 44195, USA
3Department of Hospital Medicine, Peninsula Regional Medical Center, Salisbury, MD 70118, USA
4Tulane University Health Sciences Center, Pulmonary Diseases, Critical Care and Environmental Medicine, New Orleans, LA, USA

Received 17 December 2012; Accepted 16 January 2013

Academic Editors: G. Minardi and D. Richter

Copyright © 2013 M. Chadi Alraies et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Cocaine is considered a leading cause of drug-related deaths. This is usually sudden, unwitnessed, and without prodromal features. It has been reported that in-hospital mortality is close to 2%. Cocaine has powerful central nervous system effects1 and acute cocaine overdose has been associated with hyperthermia, agitation, paranoid ideation, status epilepticus, ventricular fibrillation, ventricular tachycardia, and myocardial infarction (MI). The mechanisms of cocaine-related death remain poorly understood. We report a patient who survived massive cocaine ingestion with psychomotor agitation and generalized seizures followed by asystolic cardiac arrest and transient Brugada pattern on electrocardiogram (ECG).