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Case Reports in Cardiology
Volume 2014, Article ID 192737, 5 pages
Case Report

Hepatocellular Carcinoma to the Right Ventricle

1Division of Cardiology, University of Miami Miller School of Medicine, 1120 NW 14th Street, Clinical Research Building, Room 1107, Miami, FL 33136, USA
2Department of Internal Medicine, University of Miami Miller School of Medicine, 1611 NW 12th Avenue, Central Building, Room 600D, Miami, FL 33136, USA

Received 19 July 2014; Accepted 14 September 2014; Published 30 November 2014

Academic Editor: Tayfun Sahin

Copyright © 2014 George R. Marzouka et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Hepatocellular carcinoma (HCC) is the sixth most prevalent cancer in the world, but metastatic disease to the heart is rare. We present a case of a 63-year-old man with history of hepatitis C and cirrhosis, which had progressed to HCC. The patient had undergone two prior liver transplantations. He presented to the hospital complaining of worsening lower extremity edema. His exam was also pertinent for jugular venous distension, a 3/6 crescendo-decrescendo murmur, and hepatosplenomegaly. A transthoracic echocardiogram showed a large irregular lobulated mass in the apex of the right ventricle with a mobile pedunculated component. An MRI of the heart revealed a 4.4 × 3.4 × 4.0 cm mass within the right ventricular apex, which was subsequently biopsied and found to be moderately differentiated HCC with myocardial fragments. The patient opted out of any further therapy, or intervention, and was enrolled in hospice care.