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Case Reports in Cardiology
Volume 2015, Article ID 607107, 3 pages
Case Report

A Rare Case of Aortic Valve Thrombosis in Patient with Idiopathic Hypereosinophilic Syndrome

1Department of Cardiology, Ospedale dell’Angelo, Mestre, 30174 Venezia, Italy
2Angiology Unit, Ospedale dell’Angelo, Mestre, 30174 Venezia, Italy
3Department of Internal Medicine, Ospedale dell’Angelo, Mestre, 30174 Venezia, Italy

Received 26 June 2015; Accepted 31 August 2015

Academic Editor: Saadeh Al-Jureidini

Copyright © 2015 Elisabetta Grolla et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Idiopathic hypereosinophilic syndrome (HES) is characterized by persistent eosinophilia and eosinophil-mediated organ-system damage. Cardiac thrombosis and thromboembolic complications represent common causes of morbidity and mortality and usually involve cardiac ventricles or mitral and prosthetic valves, while the involvement of the aortic valve is extremely rare in HES. Here we report peculiar multimodality images of an atypical case of extended thrombosis of the aortic valve, complicated by myocardial ischemia and asymptomatic cerebral ischemia, likely due to thrombus embolization, occurring in a 48-year-old man with HES. Prompt anticoagulant and steroid therapy lead to rapid and complete resolution of the thrombotic lesions, allowing preserving the native valve and preventing further embolic events.