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Case Reports in Cardiology
Volume 2016, Article ID 2384752, 6 pages
Case Report

Sepsis-Induced Takotsubo Cardiomyopathy Leading to Torsades de Pointes

1Department of Medicine, SUNY Downstate Medical Center, Brooklyn, NY 11203, USA
2Department of Cardiology, VA NY Harbor Healthcare System, Brooklyn, NY 11209, USA
3College of Medicine, SUNY Downstate Medical Center, Brooklyn, NY 11203, USA
4Department of Cardiology, SUNY Downstate Medical Center, Brooklyn, NY 11203, USA

Received 22 March 2016; Revised 7 June 2016; Accepted 26 June 2016

Academic Editor: Monvadi Barbara Srichai

Copyright © 2016 Nirav Patel et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Background. Takotsubo cardiomyopathy (TCM) is sudden and reversible myocardial dysfunction often attributable to physical or emotional triggers. Case Report. We describe a 51-year-old man presented to emergency department with sepsis from urinary tract infection (UTI). He was placed on cefepime for UTI and non-ST-elevation myocardial infarction protocol given elevated troponins with chest pain. Subsequently, patient was pulseless with torsades de pointes (TdP) and then converted to sinus rhythm with cardioversion. An echocardiogram revealed low ejection fraction with hypokinesis of the apical wall. Over 48 hours, the patient was extubated and stable on 3 L/min nasal cannula. He underwent a cardiac catheterization to evaluate coronary artery disease (CAD) and was found to have mild nonobstructive CAD with no further findings. Conclusion. TCM is a rare disorder presenting with symptoms similar to acute coronary syndrome. Though traditionally elicited by physical and emotional triggers leading to transient left ventricular dysfunction, our case suggests that it may also be triggered by a urinary tract infection and lead to severe QT prolongation and a malignant ventricular arrhythmia in TdP.