Case Report | Open Access
Arteria Lusoria: An Anomalous Finding during Right Transradial Coronary Intervention
Arteria Lusoria or aberrant right subclavian artery (ARSA) is present in 0.6–1.4% of individuals. It typically remains clinically silent and is often discovered during angiographic procedures. The presence of ARSA can make a right transradial approach for coronary angiography and angioplasty technically more difficult. With the use of catheter support, we describe two cases in which a right transradial approach for catheterization was successful in the setting of ARSA. As such, the presence of ARSA does not warrant abandoning a transradial approach for coronary angiography and angioplasty.
Arteria Lusoria or aberrant right subclavian artery (ARSA) is the most common congenital arch anomaly in which the right subclavian artery originates from the descending aorta, distal to the left subclavian at the ductus arteriosus . On its course towards the right arm, the aberrant vessel travels retrotracheal and retroesophageal . The prevalence of ARSA ranges from 0.6 to 1.4% . The prevalence of ARSA rises exponentially to 26–34% in individuals with Down syndrome and other chromosomal defects .
ARSA remains clinically silent in the majority of cases. In approximately 5% of individuals, ARSA is associated with an aberrant umbilical vein, tricuspid atresia, or tetralogy of Fallot . Rarely, ARSA can accompany Kommerell’s diverticulum, an aneurysm of the descending aorta at the origin of the ARSA . This can present clinically as dysphagia, dyspnea, or subclavian steal syndrome, often requiring surgical intervention .
Despite reports of complications on right radial approach for angiography, we report two cases demonstrating the success and safety of this approach.
2. Case 1
A 42-year-old man with a past history of hypertension and hyperlipidemia, presented to hospital with acute onset of retrosternal chest discomfort. He had an elevation of his cardiac biomarkers and was diagnosed with non-ST elevation myocardial infarction (NSTEMI). During coronary angiography, right radial access with a 6 Fr. Side arm sheath was obtained. The advancement of any catheters into the ascending aorta from the radial approach was very difficult due to tortuous angulation at the junction between the ascending aorta and the right innominate artery. With the help of a 0.035′′ Glidewire (Terumo Interventional Systems, Somerset, NJ), a pigtail was advanced into the ascending aorta and an aortic root angiography was performed. This confirmed the presence of ARSA (Figure 1). For catheter exchanges, a 260 cm 0.038′′ J curved wire (Cordis, Hialeah, FL) was used. A JL3.5 diagnostic catheter (Cordis, Hialeah, FL) was used for left coronary angiography and a JR4.0 diagnostic catheter (Cordis, Hialeah, FL) was used for right coronary angiography. For the PCI procedure, a 6 Fr. XB 3.5 guiding catheter (Cordis, Hialeah, FL) was used to allow adequate support during the LAD intervention.
3. Case 2
A 51-year-old woman presented for angiography following a NSTEMI. A right radial approach with a 6 Fr. Sheath was selected. Multiple guidewires consistently engaged the descending aorta. A Judkins right 4.0 catheter (Cordis, Hialeah, FL) was placed at the right subclavian artery ostium. With gentle clockwise motion and simultaneous advancement of the 0.038′′ guidewire, the ascending aorta was successfully engaged (Figure 2). As with Case 1, catheter exchanges were done with a 260 cm 0.038′′ J curved wire (Cordis, Hialeah, FL). Angioplasty was performed using a 6 Fr. XB 4.0 guiding catheter (Cordis, Hialeah, FL). A subsequent computed tomography of the chest confirmed the diagnosis of ARSA.
In the vast majority of patients, as in the two cases illustrated, ARSA is clinically silent until right radial coronary angiography is entertained. With the increasing use of a transradial approach for coronary angiography as a result of the lower risk of access site related complications, ARSA will be encountered more frequently . ARSA can be confirmed by aortography and should be suspected when catheterization of the ascending aorta proves difficult and the catheter favors entry into the descending aorta. Due to the increased anatomical complexity, ARSA may increase number of catheters used and prolong angiography time, especially if previously unrecognized .
Previous studies have described low procedural success rates of 6/10 during catheterization in the setting of ARSA, due to increased technical demand . We have demonstrated with the two current cases that catheter support and rotation can facilitate successful, nontraumatic entry into the ascending aorta . In addition, a transradial approach in the setting of ARSA appears safe, with no significant difference in dissection rate between anatomically normal and variant subclavian arteries . As in all cases in which complex percutaneous coronary intervention is required, specific attention should be placed on appropriate guide support. In the absence of this, consideration towards gaining access from another approach would be warranted.
While right radial angiography and angioplasty are technically more demanding in the setting of ARSA, it does not necessitate abandoning the right radial approach .
The authors have conformed to institutional ethical guidelines.
Consent was obtained from patients included in the case report.
The authors report no financial relationships or conflict of interests regarding the content herein.
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Copyright © 2016 David Allen et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.