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Case Reports in Cardiology
Volume 2017 (2017), Article ID 6107327, 4 pages
Case Report

Case Report of First Angiography-Based On-Line FFR Assessment during Coronary Catheterization

Cardiac Catheterization Laboratories, Cardiology Department, Rabin Medical Center, Belinson Hospital Affiliated to the “Sackler” Faculty of Medicine, Tel Aviv University, Petah Tikva, Israel

Correspondence should be addressed to Ran Kornowski; moc.liamg@ikswonrok.nar

Received 24 April 2017; Revised 19 June 2017; Accepted 3 July 2017; Published 1 August 2017

Academic Editor: Aiden Abidov

Copyright © 2017 Ran Kornowski and Hana Vaknin-Assa. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Fractional flow reserve (FFR), an index of the hemodynamic severity of coronary stenoses, is derived from hyperemic pressure measurements and requires a pressure-monitoring guide wire and hyperemic stimulus. Although it has become the standard of reference for decision-making regarding coronary revascularization, the procedure remains underutilized due to its invasive nature. is a novel technology that uses the patient’s hemodynamic data and routine angiograms to generate a complete three-dimensional coronary tree, with color-coded display of the FFR values at each point along the vessels. After being proven to be as accurate as invasive FFR measurements in an off-line study, this case report presents the first on-line application of the system in the catheterization lab. Here too, a high concordance between and invasive FFR was observed. In light of the demonstrated capabilities of the system, it should emerge as an important tool for clinical decision-making regarding revascularization in patients with coronary artery disease.