Case Report

A Case of a 50-Year-Old Woman with Typical Fabry Disease Who Showed Serial Electrocardiographic and Echocardiographic Changes over a 17-Year Period

Table 1

Hospitalization history between 2003 and 2010.

YearAgeSymptomsEvaluation

200337Palpitation and chest discomfortECG: a normal PR interval (160 ms) and LVH (36 mm) by the Sokolow criteria with T wave inversion on V4-6 (Figure 1(b))
Thyroid function test: normal
Transthoracic echocardiography (TTE): concentric LVH
Treadmill test: normal
24-hour Holter monitoring: normal

200741Palpitation and chest discomfortECG: LVH (38 mm) by the Sokolow-Lyon index but a normal PR interval (160 ms) (Figure 1(c))
24-hour Holter monitoring: normal
Myocardial stress single-photon emission computed tomography: normal

200842Palpitation and chest discomfortECG: a short PR interval (120 ms) and marked LVH (47 mm) by the Sokolow-Lyon index (Figure 1(d))
Coronary angiography: myocardial bridging in the mid portion of the left anterior descending artery

201044Palpitation and chest discomfortECG: a short PR interval (120 ms) and marked LVH (46 ms) by the Sokolow-Lyon index (Figure 1(e))
TTE: concentric LVH (Figures 2(a) and 2(b))

ECG: electrocardiography; LVH: left ventricular hypertrophy.