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Case Reports in Critical Care
Volume 2017 (2017), Article ID 3092457, 4 pages
Case Report

Bronchopleural Fistula Resolution with Endobronchial Valve Placement and Liberation from Mechanical Ventilation in Acute Respiratory Distress Syndrome: A Case Series

1Pulmonary Department, Byrd Clinical Center, Marshall University School of Medicine, 1249 15th Street, Huntington, WV 25701, USA
2Internal Medicine Department, Marshall University School of Medicine, 1600 Medical Center Drive, Huntington, WV 25701, USA

Correspondence should be addressed to Haris Kalatoudis

Received 21 November 2016; Accepted 23 February 2017; Published 7 March 2017

Academic Editor: Kenneth S. Waxman

Copyright © 2017 Haris Kalatoudis et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Patients who have acute respiratory distress syndrome (ARDS) with persistent air leaks have worse outcomes. Endobronchial valves (EBV) are frequently deployed after pulmonary resection in noncritically ill patients to reduce and eliminate bronchopleural fistulas (BPFs) with persistent air leak (PAL). Information regarding EBV placement in mechanically ventilated patients with ARDS and high volume persistent air leaks is rare and limited to case reports. We describe three cases where EBV placement facilitated endotracheal extubation in patients with severe respiratory failure on prolonged mechanical ventilation with BPFs. In each case, EBV placement led to immediate resolution of PAL. We believe endobronchial valve placement is a safe method treating persistent air leak with severe respiratory failure and may reduce days on mechanical ventilation.